[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"article-detail":3},{"lang":4,"article":5,"alternate":19,"related":24,"latest":33},"en",{"id":6,"slug":7,"title":8,"content":9,"summary":10,"thumbnail":11,"metaDescription":12,"metaKeywords":13,"created":14,"modified":14,"author":15,"authorEn":15,"categoryId":16,"commentCount":17,"thumbnailToContent":18},13292,"shamonda-virus-human-first-case-oorw","Shamonda Virus: The First Human Case Ever Reported","\u003Cp style=\"margin:0 0 18px;\">For six decades, Shamonda virus stayed quietly inside cattle. Then, on 22 October 2026, French health and agriculture authorities announced the first human infection ever documented: a severely immunocompromised patient treated in Lyon, who died in early October.\u003C\u002Fp>\n\u003Cp style=\"margin:0 0 18px;\">\u003Cstrong>A first case, with questions still open\u003C\u002Fstrong>\u003C\u002Fp>\n\u003Cp style=\"margin:0 0 18px;\">The joint statement reported the first formally recorded human infection with Shamonda virus (SHAV). The patient was being treated in Lyon for a serious illness that had left them severely immunocompromised, and died in early October.\u003C\u002Fp>\n\u003Cp style=\"margin:0 0 18px;\">Preliminary investigations suggest that brain complications before the patient's death were very likely linked to the infection. But the European Centre for Disease Prevention and Control (ECDC) stresses that whether the virus caused or contributed to the death — and how the infection was acquired — is still under investigation.\u003C\u002Fp>\n\u003Cp style=\"margin:0 0 18px;\">\u003Cstrong>What the Shamonda virus is\u003C\u002Fstrong>\u003C\u002Fp>\n\u003Cp style=\"margin:0 0 18px;\">Shamonda virus is an orthobunyavirus in the Simbu serogroup: a segmented, negative-sense single-stranded RNA virus with three segments, L, M and S. It was first isolated from cattle in Nigeria in the mid-1960s, and has since been reported sporadically in cattle in parts of Africa and in Japan. Cattle are considered its main host.\u003C\u002Fp>\n\u003Cp style=\"margin:0 0 18px;\">\u003Cimg src=\"\u002Fattachment\u002F20261024\u002F2cda3776afb24efd9c80ec81a527c188.webp\" alt=\"img_03.webp\">\u003C\u002Fp>\n\u003Cfigure class=\"table\">\n \u003Ctable style=\"border-collapse:collapse;color:#333;font-size:14px;margin:18px 0;max-width:680px;width:100%;\">\n  \u003Ctbody>\n   \u003Ctr>\n    \u003Cth style=\"background-color:#f7f7f7;border:1px solid #ddd;padding:9px 10px;text-align:left;\">Shamonda virus at a glance\u003C\u002Fth>\n    \u003Cth style=\"background-color:#f7f7f7;border:1px solid #ddd;padding:9px 10px;text-align:left;\">Facts\u003C\u002Fth>\n   \u003C\u002Ftr>\n   \u003Ctr>\n    \u003Cth style=\"border:1px solid #ddd;padding:9px 10px;\">Classification\u003C\u002Fth>\n    \u003Cth style=\"border:1px solid #ddd;padding:9px 10px;\">Orthobunyavirus of the Simbu serogroup; segmented, negative-sense single-stranded RNA genome in three segments (L, M, S)\u003C\u002Fth>\n   \u003C\u002Ftr>\n   \u003Ctr>\n    \u003Cth style=\"border:1px solid #ddd;padding:9px 10px;\">First isolated\u003C\u002Fth>\n    \u003Cth style=\"border:1px solid #ddd;padding:9px 10px;\">1965, from cattle in Nigeria; later detected in cattle, sheep and Culicoides midges in Japan and South Africa\u003C\u002Fth>\n   \u003C\u002Ftr>\n   \u003Ctr>\n    \u003Cth style=\"border:1px solid #ddd;padding:9px 10px;\">Transmission\u003C\u002Fth>\n    \u003Cth style=\"border:1px solid #ddd;padding:9px 10px;\">Bites from blood-feeding midges of the genus Culicoides — an arbovirus\u003C\u002Fth>\n   \u003C\u002Ftr>\n   \u003Ctr>\n    \u003Cth style=\"border:1px solid #ddd;padding:9px 10px;\">Effects on animals\u003C\u002Fth>\n    \u003Cth style=\"border:1px solid #ddd;padding:9px 10px;\">Fever, lower milk yield, reproductive losses; 2015–2016 — SHAV confirmed in 15 malformed calves in Japan with arthrogryposis and CNS lesions\u003C\u002Fth>\n   \u003C\u002Ftr>\n   \u003Ctr>\n    \u003Cth style=\"border:1px solid #ddd;padding:9px 10px;\">Relationship to Schmallenberg virus (SBV)\u003C\u002Fth>\n    \u003Cth style=\"border:1px solid #ddd;padding:9px 10px;\">SBV is likely its ancestor: SHAV appears to be a reassortant carrying SBV's S and L segments plus an M segment from an unclassified virus — M segment nucleotide identity is only 48.2%\u003C\u002Fth>\n   \u003C\u002Ftr>\n   \u003Ctr>\n    \u003Cth style=\"border:1px solid #ddd;padding:9px 10px;\">Human risk\u003C\u002Fth>\n    \u003Cth style=\"border:1px solid #ddd;padding:9px 10px;\">First human case reported in France, 2026 — a severely immunocompromised patient who died; a single exceptional case, no evidence of broad human disease or person-to-person spread\u003C\u002Fth>\n   \u003C\u002Ftr>\n  \u003C\u002Ftbody>\n \u003C\u002Ftable>\n\u003C\u002Ffigure>\n\u003Cp style=\"margin:0 0 18px;\">\u003Cstrong>A bite from a biting midge\u003C\u002Fstrong>\u003C\u002Fp>\n\u003Cp style=\"margin:0 0 18px;\">Shamonda virus is an arbovirus: it spreads between animals through bites from blood-feeding midges of the genus \u003Ci>Culicoides\u003C\u002Fi>. French authorities suspect the patient was bitten by an infected midge in eastern France, a territory where the virus circulated in animals during spring and summer 2026. The specific midge species involved in this case has yet to be confirmed.\u003C\u002Fp>\n\u003Cp style=\"margin:0 0 18px;\">\u003Cimg src=\"\u002Fattachment\u002F20261024\u002F8e9a22ec6d3b4b05b43e360948704e15.webp\" alt=\"img_02.webp\">\u003C\u002Fp>\n\u003Cp style=\"margin:0 0 18px;\">\u003Cstrong>The jump to Europe in 2026\u003C\u002Fstrong>\u003C\u002Fp>\n\u003Cp style=\"margin:0 0 18px;\">Summer 2026 brought the virus's first detection in European farm animals: clinical signs were reported from June, and the virus was identified in late July. It has since been found in farm animals in Austria, Belgium, France, Germany, Ireland, Italy, Liechtenstein, Luxembourg, the Netherlands, Portugal, Spain, Switzerland and Jersey.\u003C\u002Fp>\n\u003Cp style=\"margin:0 0 18px;\">\u003Cimg src=\"\u002Fattachment\u002F20261024\u002F158cc63bfd1f42b4aff4e87b79d435d7.webp\" alt=\"img_01.webp\">\u003C\u002Fp>\n\u003Cp style=\"margin:0 0 18px;\">\u003Cstrong>What the risk is\u003C\u002Fstrong>\u003C\u002Fp>\n\u003Cp style=\"margin:0 0 18px;\">French authorities describe the case as exceptional, occurring in a severely immunocompromised patient. Based on current knowledge, no public health risk to the general population has been identified. ECDC is working with the relevant EU reference laboratory to strengthen testing capacity and support member states in identifying any other potential cases.\u003C\u002Fp>\n\u003Cp style=\"margin:0 0 18px;\">Shamonda virus spent sixty years infecting cattle before a single patient in Lyon showed that the list of species it can reach is longer than anyone had recorded. It travels on the mouthparts of insects you barely notice — which is a good reason to look closely at what blood-feeding insects actually look like.\u003C\u002Fp>\n\u003Cp style=\"margin:0 0 18px;\">Want to see the kind of insect that carries viruses like this one? With WWAI, you can examine a \u003Cstrong>Culex Mosquito specimen\u003C\u002Fstrong> under a virtual microscope — segmented body, wing venation and piercing mouthparts — the moment curiosity strikes, with no physical microscope needed. Just search \"WWAI\" in your app store to download.\u003C\u002Fp>\n\u003Cdiv class=\"dp-template-card\" style=\"border-radius:8px;box-shadow:0 2px 8px rgba(0,0,0,0.1);margin:10px 0;max-width:100%;overflow:hidden;width:100%;\">\n \u003Ca style=\"display:block;text-decoration:none;\" href=\"https:\u002F\u002Fyun-hub.chat\u002Flink\u002F?app=wwai&clickid=stellarx&dplink=specimenid%3D1076\" target=\"_blank\">\u003Cimg class=\"image_resized\" style=\"display:block;height:auto;max-width:100%;width:100%;\" src=\"\u002Fattachment\u002F20260824\u002F5ba5dd3c38404fe785f43c44423830de.png\" alt=\"5ba5dd3c38404fe785f43c44423830de\">\n  \u003Cbutton style=\"align-items:center;background-color:#1f983e;border-radius:0 0 25px 25px;border-style:none;color:#ffffff;cursor:pointer;display:flex;font-family:Times New Roman;font-size:19px;height:40px;justify-content:center;padding:0;width:100%;\">EXPLORE NOW\u003C\u002Fbutton>\u003C\u002Fa>\n\u003C\u002Fdiv>\n\u003Cp style=\"color:#111;margin:28px 0 8px;\">\u003Cstrong>Related reading\u003C\u002Fstrong>\u003C\u002Fp>\n\u003Cp style=\"margin:0 0 20px;\">\u003Ca style=\"color:#111;text-decoration:none;\" href=\"https:\u002F\u002Fstellarx.tech\u002Farticle\u002Frabies-vaccine-why-it-matters\">\u003Cimg class=\"image_resized\" style=\"border-radius:8px;display:block;height:auto;margin-bottom:6px;max-width:520px;width:100%;\" src=\"https:\u002F\u002Fcdn.banyunjuhe.com\u002Fattachment\u002F20260929\u002Fcbb7bfb340c34b378a26e83396b82b6f.png\" alt=\"Why Skipping the Rabies Shot Can Kill You\">\u003C\u002Fa>\u003Cbr>\u003Ca style=\"color:#0b6cb0;text-decoration:none;\" href=\"https:\u002F\u002Fstellarx.tech\u002Farticle\u002Frabies-vaccine-why-it-matters\">\u003Cstrong>Why Skipping the Rabies Shot Can Kill You\u003C\u002Fstrong>\u003C\u002Fa>\u003C\u002Fp>\n\u003Cp style=\"margin:0 0 20px;\">\u003Ca style=\"color:#111;text-decoration:none;\" href=\"https:\u002F\u002Fstellarx.tech\u002Farticle\u002Fmosquito-blood-not-food-iznb\">\u003Cimg class=\"image_resized\" style=\"border-radius:8px;display:block;height:auto;margin-bottom:6px;max-width:520px;width:100%;\" src=\"https:\u002F\u002Fcdn.banyunjuhe.com\u002Fattachment\u002F20261015\u002F0e362d2054c84eb8a3914c0ee2abb6b9.webp\" alt=\"Why Mosquitoes Drink Blood — It's Not for Dinner\">\u003C\u002Fa>\u003Cbr>\u003Ca style=\"color:#0b6cb0;text-decoration:none;\" href=\"https:\u002F\u002Fstellarx.tech\u002Farticle\u002Fmosquito-blood-not-food-iznb\">\u003Cstrong>Why Mosquitoes Drink Blood — It's Not for Dinner\u003C\u002Fstrong>\u003C\u002Fa>\u003C\u002Fp>\n\u003Cp style=\"margin:0 0 20px;\">\u003Ca style=\"color:#111;text-decoration:none;\" href=\"https:\u002F\u002Fstellarx.tech\u002Farticle\u002Falpha-gal-syndrome-gmht\">\u003Cimg class=\"image_resized\" style=\"border-radius:8px;display:block;height:auto;margin-bottom:6px;max-width:520px;width:100%;\" src=\"https:\u002F\u002Fcdn.banyunjuhe.com\u002Fattachment\u002F20261001\u002Faa24a6f7e36b4b2fb5b8a0f6c3bfd1d8.webp\" alt=\"Alpha-Gal Syndrome: The Tick-Borne Meat Allergy\">\u003C\u002Fa>\u003Cbr>\u003Ca style=\"color:#0b6cb0;text-decoration:none;\" href=\"https:\u002F\u002Fstellarx.tech\u002Farticle\u002Falpha-gal-syndrome-gmht\">\u003Cstrong>Alpha-Gal Syndrome: The Tick-Borne Meat Allergy\u003C\u002Fstrong>\u003C\u002Fa>\u003C\u002Fp>\n\u003Ch2 style=\"color:#111;font-size:21px;line-height:1.4;margin:28px 0 12px;\">\u003Cstrong>References\u003C\u002Fstrong>\u003C\u002Fh2>\n\u003Cp style=\"margin:0 0 18px;\">European Centre for Disease Prevention and Control (ECDC). \u003Ci>Severely ill patient in France becomes first ever human infected with Shamonda virus.\u003C\u002Fi> 22 October 2026. https:\u002F\u002Fwww.ecdc.europa.eu\u002Fen\u002Fnews-events\u002Fseverely-ill-patient-france-becomes-first-ever-human-infected-shamonda-virus\u003C\u002Fp>\n\u003Cp style=\"margin:0 0 18px;\">Kelleci M, et al. \u003Ci>Detection of a novel Shamonda Orthobunyavirus in dairy cattle, France, June 2026.\u003C\u002Fi> Euro Surveill. 2026;31(33):2600689. https:\u002F\u002Fpmc.ncbi.nlm.nih.gov\u002Farticles\u002FPMC13498902\u002F\u003C\u002Fp>\n\u003Cp style=\"margin:0 0 18px;\">Goller KV, et al. \u003Ci>Schmallenberg Virus as Possible Ancestor of Shamonda Virus.\u003C\u002Fi> Emerg Infect Dis. 2012. https:\u002F\u002Fpmc.ncbi.nlm.nih.gov\u002Farticles\u002FPMC3471646\u002F\u003C\u002Fp>","","\u002Fattachment\u002F20261024\u002Fcca332db12bf4ecba2c27f36c2314d77.webp","France has reported the first ever human infection with Shamonda virus. What is this biting-midge-borne orthobunyavirus — and what is the risk?","stellarx, wwai, shamonda virus, orthobunyavirus, biting midge, first human case","2026-10-24 22:38:31","Science Guide Wwai",77,0,false,{"id":20,"slug":21,"title":22,"lang":23},13291,"shamonda-first-human-infection-france-mqag","沙蒙達病毒：全球首例人類感染病例","zh",{"prev":25,"next":29},{"id":26,"slug":27,"title":28,"categoryId":16},13294,"fish-plastic-bag-survival-akny","Why Fish in a Plastic Bag Beat Fish in a Bucket",{"id":30,"slug":31,"title":32,"categoryId":16},13290,"vegetable-nutrition-rankings-mnpw","Vegetable Nutrition: Why Lettuce Isn't the Healthiest Green",[34,36,37,39],{"id":26,"slug":27,"title":28,"thumbnail":35,"categoryId":16},"\u002Fattachment\u002F20261024\u002F7c85c8853f4c4b26bd51a1d2b6333c4d.webp",{"id":6,"slug":7,"title":8,"thumbnail":11,"categoryId":16},{"id":30,"slug":31,"title":32,"thumbnail":38,"categoryId":16},"\u002Fattachment\u002F20261024\u002F7338aab6261d41bba05bdeb1a3dde8df.webp",{"id":40,"slug":41,"title":42,"thumbnail":43,"categoryId":16},13288,"metformin-healthspan-cancer-hbsk","Metformin for Healthspan: Muscle, Bone, and a Tumor Switch","\u002Fattachment\u002F20261024\u002F7b4ae761b4fa4f54aa0e396eafa732df.webp"]